Pharmacy Junk Mail In More Than One Sense Of The Word. Look How Much Better Glumetza® Is Than Regular Metformin

I mean seriously, just look at this graph. You'd have to be stupid not to realize how much better Glumetza™ is.

You probably don't even need or want to be told at this point that Glumetza™ is simply an extended-release version of the diabetes medicine metformin, which also goes by the brand name Glucophage. It doesn't matter. Look at the graph. Glumetza is way better. That's why the Glumetza® bar is orange and the numbers at the top are way bigger. Because Glumetza® is obviously way better.

Santaris Inc. and Depomed, the makers of Glumetza® would like you to stop reading now. They would also like you to not notice or pay attention to the top of the graph, where it clearly says that they used a daily dose 33% higher to get that pretty orange bar.

Or at the very least, they would not like you to think about how maybe it's not all that surprising that when you give a dose of a drug that is higher, it might be more effective.

Here are some other tidbits from the text of the same Glumetza® ad:

Unlike generic immediate-release metformins, Glumetza® uses advanced polymer technology, which provides controlled release of metformin targeting the upper GI system. As a result, more drug enters the bloodstream and less unabsorbed drug remains in the lower GI tract. This may help reduce GI adverse events.

I see. Well I think Glumetza ® may make your penis fall off. And I have provided as much proof for this claim as Santaris Inc. and Depomed have for theirs.

In the clinical trial above, Glumetza® was well tolerated at higher doses. The overall incidence of drug related AEs (adverse effects) was 35% for Glucophage 1500mg/day BID and 33% for Glumetza® dosed up to 2000mg QD.

Sweet. A 2% reduction of the chance of any side effects is totally worth paying $190 extra dollars a month for. Which is what Glumetza® will set you back as opposed to the dirt cheap metformin.

The regular metformin's bar in the graph isn't orange though.

Less than 1% Glumetza® patients discontinued treatment due to GI AEs in the first week of the study, when the assigned dose was 1000mg/day.

Except that pretty orange bar was for a dose of 2000mg/day. Santaris Inc. and Depomed don't seem to want to mention how many people discontinued treatment at this dose. So I'll just assume it's somewhere around 95%.

Sigh. You know, the fact that a drug manufacturer massages some numbers around isn't what bothers me here. Drug manufacturers have massaged numbers around at least since I was a drunken frat boy. They used to be far sneakier about it though. Now it's like they don't even care, and I miss being respected enough that they would at least try to spray some Lysol on their bullshit. These days it's like Big Pharma is giving bulls a special diet to make their shit extra stinky or something.

And evidently extra stinky bullshit works on someone out there. Because I filled a prescription for Glumetza® yesterday. That's what bothers me.


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Pharmacy Junk Mail In More Than One Sense Of The Word. Look How Much Better Glumetza® Is Than Regular Metformin
Pharmacy Junk Mail In More Than One Sense Of The Word. Look How Much Better Glumetza® Is Than Regular Metformin
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