Savella.™ The Wonder Drug That Works The Wonder Of Emptying Your Wallet For Little Apparent Gain.

I'm excited about the upcoming release of Savella™ (milnacipran), the new drug from Forest Laboratories and Cypress Bioscience to combat the suddenly oh-so-fashionable plague of fibromyalgia. I'm not excited because Savella offers the prospect of relief mind you, but for precisely the opposite reason. Something tells me this med is gonna warrant the unveiling of the hottest sales reps ever in order to convince much of anyone to actually write a prescription for it, and hot sales reps are cause for excitement in the happy pill room. If you saw the customers I have to look at all day long you'd know why. From The Rx Consultant, which for some reason gets mailed to me every month. I have never once to my knowledge asked for a copy of The Rx Consultant.  Maybe I subscribed when I was drunk or something. That would be depressing. Getting drunk and subscribing to trade journals. At any rate:

In the 15 week trial, response rates were about 19% in both milnacipran groups and 12% in the placebo group. At the 15 week point in the longer study, response rates with milnacipran (both doses) and placebo were about 15% and 9%, respectively....At 27 weeks, however, there was no significant difference between milnacipran and placebo.

Now I know what the fibromyalgics amongst you are saying; Wow! A 7% chance this stuff will work better than a placebo! And a whole 6 months before there's no difference from placebo at all! Tell me more!*

Happily:

The most common adverse effects of milnacipran, compared to placebo, have been nausea (37% vs. 20%) ... constipation (16% vs. 4%),  hot flush (12% vs. 2%)....

So.......lets recap. You ask your doctor if Savella™ is right for you, and if he decides it is, he'll hand you a prescription for something that's over twice as likely to make you feel like puking than it is to give you any relief. About 25% of people in the clinical trials of Savella™ dropped out because they couldn't handle the side effects by the way.

Oh, and it blew some people's livers out too. No word yet on how much Savella™ will cost, but I mean really, can you put a price on the value this type of thing adds to the practice of medicine? Hell, I wish I had fibromyalgia now so I could get me some of this action.  Actually, I think I do, since the most common way to diagnose fibromyalgia is for the patient to announce they have it, yes, I definitely do. 

On second thought never mind, I'll just look forward to seeing the sales reps. 

*You and I both know this is wrong. Most of the fibromyalgics among us are probably saying things like, "Bring me some ho-ho's!!" or "My dog ate my Vicodin!!," but for the sake of this post I'm pretending like fibromyalgia is a real condition. 



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Savella.™ The Wonder Drug That Works The Wonder Of Emptying Your Wallet For Little Apparent Gain.
Savella.™ The Wonder Drug That Works The Wonder Of Emptying Your Wallet For Little Apparent Gain.
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